The S100A11 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to S100A11. This antibody recognizes Human, Mouse, and Rat antigen. The S100A11 Antibody has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
Description: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.
Function: Facilitates the differentiation and the cornification of keratinocytes.
Subunit Structure: Homodimer; disulfide-linked.
Post-translational Modifications: Phosphorylation at Thr-10 by PRKCA significantly suppresses homodimerization and promotes association with NCL/nucleolin which induces nuclear translocation.
Similarity: Belongs to the S-100 family